Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00110)
Xenobiotics Name
Acetylcysteine
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
12035
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Azoreductase (azoR) DME Info Streptococcus pyogenes [1]
Beta-lactamase (blaB) DME Info Corynebacterium acnes [1]
Catalase (CAT) DME Info Homo sapiens [2]
Cytochrome P450 125A3 (cyp125) DME Info Mycolicibacterium smegmatis [1]
Cytochrome P450 142A2 (cyp142) DME Info Mycolicibacterium smegmatis [1]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1]
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [3]
DME(s) Induced by This Xenobiotics
NADH-ubiquinone oxidoreductase 20 kDa (NDUFS7) DME Info Homo sapiens [4]
References
1 N-acetylcysteine inhibits growth, adhesion and biofilm formation of Gram-positive skin pathogens. Microb Pathog. 2017 Apr;105:145-152.
2 Effect of N-acetylcysteine administration on the expression and activities of antioxidant enzymes and the malondialdehyde level in the blood of lead-exposed workers. Environ Toxicol Pharmacol. 2014 Mar;37(2):638-47.
3 Molecular mechanisms of action of angiopreventive anti-oxidants on endothelial cells: microarray gene expression analyses. Mutat Res. 2005 Dec 11;591(1-2):198-211.
4 N-acetylcysteine, coenzyme Q10 and superoxide dismutase mimetic prevent mitochondrial cell dysfunction and cell death induced by d-galactosamine in primary culture of human hepatocytes. Chem Biol Interact. 2009 Sep 14;181(1):95-106.

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