Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01284)
Xenobiotics Name
Dust
Xenobiotics Type
Natural Product(s), Extract(s) or Medicine(s)
Classification
Natural Mixture
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Aldehyde dehydrogenase 2 (ALDH2) DME Info Homo sapiens [1]
Catalase (CAT) DME Info Homo sapiens [1]
Catechol O-methyltransferase (COMT) DME Info Homo sapiens [1]
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [2]
Cytochrome P450 1B1 (CYP1B1) DME Info Homo sapiens [2]
Microsomal glutathione S-transferase 2 (MGST2) DME Info Homo sapiens [1]
Metallothionein-2A (MT2A) DME Info Homo sapiens [1]
Thymidine phosphorylase (TYMP) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Cytochrome P450 1A2 (CYP1A2) DME Info Homo sapiens [3]
Metallothionein-1A (MT1A) DME Info Homo sapiens [1]
Quinone reductase 1 (NQO1) DME Info Homo sapiens [1]
NADPH-cytochrome P450 reductase (CPR) DME Info Homo sapiens [1]
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [1]
Putrescine acetyltransferase (SSAT1) DME Info Homo sapiens [1]
UDP-glucuronosyltransferase 2B10 (UGT2B10) DME Info Homo sapiens [1]
UDP-glucuronosyltransferase 2B4 (UGT2B4) DME Info Homo sapiens [1]
References
1 Differential response of Mono Mac 6, BEAS-2B, and Jurkat cells to indoor dust. Environ Health Perspect. 2007 Sep;115(9):1325-32.
2 Urban dust particulate matter alters PAH-induced carcinogenesis by inhibition of CYP1A1 and CYP1B1. Toxicol Sci. 2007 Jan;95(1):63-73.
3 Asian dust storm particles induce a broad toxicological transcriptional program in human epidermal keratinocytes. Toxicol Lett. 2011 Jan 15;200(1-2):92-9.

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