Detail Information of Xenobiotics
| General Information of Xenobiotics (ID: XEO01348) | ||||||
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| Xenobiotics Name |
K-7174
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| Xenobiotics Type |
Pharmaceutical Agent(s)
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| Classification |
Preclinical/Patented Drug
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| Structure |
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| 3D MOL | 2D MOL | |||||
| PubChem CID | ||||||
| DME(s) Modulated by This Xenobiotics | ||||||
| DME(s) Inhibited by This Xenobiotics | ||||||
| Alcohol dehydrogenase class-III (ADH5) | DME Info | Homo sapiens | [1] | |||
| Porphobilinogen synthase (ALAD) | DME Info | Homo sapiens | [1] | |||
| Aldehyde dehydrogenase 1 (ALDH1) | DME Info | Homo sapiens | [1] | |||
| Aldehyde dehydrogenase 5 (ALDHX) | DME Info | Homo sapiens | [1] | |||
| Alanyl aminopeptidase (ANPEP) | DME Info | Homo sapiens | [1] | |||
| Arsenite methyltransferase (AS3MT) | DME Info | Homo sapiens | [1] | |||
| Catalase (CAT) | DME Info | Homo sapiens | [1] | |||
| Choline dehydrogenase (CHDH) | DME Info | Homo sapiens | [1] | |||
| Catechol O-methyltransferase (COMT) | DME Info | Homo sapiens | [1] | |||
| Microsomal cytochrome MCB5 (CYB5A) | DME Info | Homo sapiens | [1] | |||
| DOPA decarboxylase (DDC) | DME Info | Homo sapiens | [1] | |||
| Dihydrofolate reductase (DHFR) | DME Info | Homo sapiens | [1] | |||
| Dehydropeptidase-I (DPEP1) | DME Info | Homo sapiens | [1] | |||
| Dipeptidyl peptidase IV (DPP4) | DME Info | Homo sapiens | [1] | |||
| Thymidylate kinase (DTYMK) | DME Info | Homo sapiens | [1] | |||
| Bifunctional epoxide hydrolase 2 (EPHX2) | DME Info | Homo sapiens | [1] | |||
| Fatty acid desaturase 2 (FADS2) | DME Info | Homo sapiens | [1] | |||
| Galactose kinase (GALK1) | DME Info | Homo sapiens | [1] | |||
| Glutamyl-tRNA(Gln) amidotransferase B (GATB) | DME Info | Homo sapiens | [1] | |||
| Gamma-Glu-X carboxypeptidase (GGH) | DME Info | Homo sapiens | [1] | |||
| Glutathione S-transferase alpha-1 (GSTA1) | DME Info | Homo sapiens | [1] | |||
| Glutathione S-transferase alpha-2 (GSTA2) | DME Info | Homo sapiens | [1] | |||
| Glutathione S-transferase omega-2 (GSTO2) | DME Info | Homo sapiens | [1] | |||
| Glutathione S-transferase theta-1 (GSTT1) | DME Info | Homo sapiens | [1] | |||
| Histamine N-methyltransferase (HNMT) | DME Info | Homo sapiens | [1] | |||
| Keto-steroid reductase (HSD17B7) | DME Info | Homo sapiens | [1] | |||
| Kynurenine aminotransferase I (KYAT1) | DME Info | Homo sapiens | [1] | |||
| Methionine-tRNA ligase mitochondrial (MARS2) | DME Info | Homo sapiens | [1] | |||
| S-adenosylmethionine synthase 1 (MAT1A) | DME Info | Homo sapiens | [1] | |||
| Microsomal glutathione S-transferase 2 (MGST2) | DME Info | Homo sapiens | [1] | |||
| Peptide methionine sulfoxide reductase (MSRA) | DME Info | Homo sapiens | [1] | |||
| Methionine-R-sulfoxide reductase B1 (MSRB1) | DME Info | Homo sapiens | [1] | |||
| Metallothionein-1A (MT1A) | DME Info | Homo sapiens | [1] | |||
| Metallothionein-2A (MT2A) | DME Info | Homo sapiens | [1] | |||
| RNA cytidine acetyltransferase (hALP) | DME Info | Homo sapiens | [1] | |||
| NADH-ubiquinone oxidoreductase 30 kDa (NDUFS3) | DME Info | Homo sapiens | [1] | |||
| Phosphorylethanolamine transferase (PCYT2) | DME Info | Homo sapiens | [1] | |||
| Phosphoglucomutase 1 (PGM1) | DME Info | Homo sapiens | [1] | |||
| Serum paraoxonase/lactonase 3 (PON3) | DME Info | Homo sapiens | [1] | |||
| Selenocysteine lyase (SCLY) | DME Info | Homo sapiens | [1] | |||
| Superoxide dismutase 1 (SOD1) | DME Info | Homo sapiens | [1] | |||
| Steroid 5-alpha-reductase 3 (SRD5A3) | DME Info | Homo sapiens | [1] | |||
| Sulfotransferase 2A1 (SULT2A1) | DME Info | Homo sapiens | [1] | |||
| Thymidylate synthase (TYMS) | DME Info | Homo sapiens | [1] | |||
| UDP-glucuronosyltransferase 2A3 (UGT2A3) | DME Info | Homo sapiens | [1] | |||
| Uridine 5'-monophosphate synthase (UMPS) | DME Info | Homo sapiens | [1] | |||
| Vitamin K1 2,3-epoxide reductase 1 (VKOR) | DME Info | Homo sapiens | [1] | |||
| DME(s) Induced by This Xenobiotics | ||||||
| Small intestine reductase (AKR1B10) | DME Info | Homo sapiens | [1] | |||
| Aldo-keto reductase 1C2 (AKR1C2) | DME Info | Homo sapiens | [1] | |||
| Asparagine synthetase (ASNS) | DME Info | Homo sapiens | [1] | |||
| Cytosolic branched aminotransferase (BCAT1) | DME Info | Homo sapiens | [1] | |||
| Serine sulfhydrase (CBS) | DME Info | Homo sapiens | [1] | |||
| Carboxylesterase 1 (CES1) | DME Info | Homo sapiens | [1] | |||
| Short-chain dehydrogenase/reductase retSDR1 (DHRS3) | DME Info | Homo sapiens | [1] | |||
| Glutathione reductase (GSR) | DME Info | Homo sapiens | [1] | |||
| N-acetyl-beta-glucosaminidase beta (HEXB) | DME Info | Homo sapiens | [1] | |||
| Prostaglandin reductase 1 (PTGR1) | DME Info | Homo sapiens | [1] | |||
| Putrescine acetyltransferase (SSAT1) | DME Info | Homo sapiens | [1] | |||
| Thioredoxin reductase TR1 (TXNRD1) | DME Info | Homo sapiens | [1] | |||
| References | ||||||
| 1 | A low-molecular-weight compound K7174 represses hepcidin: possible therapeutic strategy against anemia of chronic disease. PLoS One. 2013 Sep 27;8(9):e75568. | |||||
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