Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01605)
Xenobiotics Name
Pentachlorophenol
Xenobiotics Type
Fungicide(s), Herbicide(s) or Insecticide(s)
Classification
Pesticide/Insecticide
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=992"></iframe>
3D MOL 2D MOL
PubChem CID
992
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Dihydrotestosterone oxidoreductase (HSD3B1) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [2], [3]
Cytochrome P450 2B6 (CYP2B6) DME Info Homo sapiens [3]
Cytochrome P450 3A4 (CYP3A4) DME Info Homo sapiens [2]
Cytochrome P450 3A7 (CYP3A7) DME Info Homo sapiens [3]
NADPH-cytochrome P450 reductase (CPR) DME Info Homo sapiens [1]
UDP-glucuronosyltransferase 1A10 (UGT1A10) DME Info Homo sapiens [1]
References
1 A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors. Arch Toxicol. 2015 Sep;89(9):1599-618.
2 Transcriptome analysis of airborne PM2.5-induced detrimental effects on human keratinocytes. Toxicol Lett. 2017 May 5;273:26-35.
3 Identification of approved drugs as potent inhibitors of pregnane X receptor activation with differential receptor interaction profiles. Arch Toxicol. 2018 Apr;92(4):1435-1451.

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