Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO02780)
Xenobiotics Name
Cefixime
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
5362065
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Beta-lactamase (blaB) DME Info Klebsiella variicola [1]
Beta-lactamase (blaB) DME Info Klebsiella aerogenes [1]
Metallo-beta-lactamase (blaM) DME Info Klebsiella pneumoniae [1]
Beta-lactamase (blaB) DME Info Klebsiella pneumoniae [1]
Cytidine deaminase (cdd) DME Info Escherichia coli [1]
Cytidine deaminase (cdd) DME Info Klebsiella pneumoniae [1]
Unclear metabolic mechanism (DME-unclear) DME Info Klebsiella pneumoniae [1]
Unclear metabolic mechanism (DME-unclear) DME Info Streptococcus mutans [1]
Glutamate decarboxylase (gadB) DME Info Listeria monocytogenes [2]
Molybdopterin-dependent enzyme (molD) DME Info Klebsiella pneumoniae [1]
Methylthioribose kinase (mtnK) DME Info Klebsiella pneumoniae [1]
S-adenosylhomocysteine nucleosidase (mtnN) DME Info Klebsiella pneumoniae [1]
Glutamate racemase (MurI) DME Info Streptococcus mutans [1]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1]
NADPH-dependent nitroreductase (nfrA1) DME Info Bacillus subtilis [3]
Arylamine N-acetyltransferase (NAT) DME Info Klebsiella pneumoniae [1]
Glutamate racemase (MurI) DME Info Bacillus subtilis [3]
Glutamate racemase (MurI) DME Info Bacillus pumilus [3]
General stress protein 14 (ywrO) DME Info Bacillus subtilis [3]
References
1 Antibiofilm potential of 16-oxo-cleroda-3, 13(14) E-diene-15 oic acid and its five new gama-amino gama-lactone derivatives against methicillin resistant Staphylococcus aureus and Streptococcus mutans. Eur J Med Chem. 2017 Sep 29;138:480-490.
2 Role of PBPD1 in stimulation of Listeria monocytogenes biofilm formation by subminimal inhibitory beta-lactam concentrations. Antimicrob Agents Chemother. 2014 Nov;58(11):6508-17.
3 Examine the characterization of biofilm formation and inhibition by targeting SrtA mechanism in Bacillus subtilis: a combined experimental and theoretical study. J Mol Model. 2014 Aug;20(8):2364.

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