Details of Microbiome-DME Interaction (MICBIO)

General Information of Drug-Metabolizing Enzyme (DME ID: DME0075)
DME Name UDP-glucuronosyltransferase 1A10 (UGT1A10), Homo sapiens DME Info
UniProt ID
UD110_HUMAN
EC Number    EC: 2.4.1.17     (Click to Show/Hide the Complete EC Tree)
Transferase
Glycosyltransferases
Hexosyltransferase
EC: 2.4.1.17
Lineage    Species: Homo sapiens     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
Interactome
Interactions between Microbiome and DME (MICBIO)
      Bacteria: Actinobacteria
                  Bifidobacterium adolescentis (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bifidobacterium adolescentis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bifidobacterium breve (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bifidobacterium breve co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bifidobacterium longum (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bifidobacterium longum co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bifidobacterium ruminatum (actinobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bifidobacterium ruminatum co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bifidobacterium ruminatum co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Collinsella intestinalis (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Collinsella intestinalis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Eggerthella lenta (actinobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Eggerthella lenta co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
      Bacteria: Bacteroidetes
                  Alistipes indistinctus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Alistipes indistinctus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bacteroides coprophilus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides coprophilus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bacteroides dorei (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides dorei co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides dorei co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bacteroides eggerthii (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides eggerthii co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bacteroides fragilis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Etodolac Click to Show/Hide the Detail
                                 Drug ID DR0666   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides fragilis co-metabolize the drug Etodolac, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides fragilis co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides fragilis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides fragilis co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                  Bacteroides intestinalis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides intestinalis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bacteroides ovatus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides ovatus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bacteroides sartorii (CFB bacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Etodolac Click to Show/Hide the Detail
                                 Drug ID DR0666   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides sartorii co-metabolize the drug Etodolac, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides sartorii co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides sartorii co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides sartorii co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                  Bacteroides stercoris (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides stercoris co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bacteroides thetaiotaomicron (CFB bacteria) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Etodolac Click to Show/Hide the Detail
                                 Drug ID DR0666   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides thetaiotaomicron co-metabolize the drug Etodolac, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides thetaiotaomicron co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides thetaiotaomicron co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                  Bacteroides uniformis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides uniformis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bacteroides vulgatus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides vulgatus co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides vulgatus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides vulgatus co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                  Bacteroides xylanisolvens (CFB bacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Etodolac Click to Show/Hide the Detail
                                 Drug ID DR0666   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides xylanisolvens co-metabolize the drug Etodolac, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides xylanisolvens co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides xylanisolvens co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides xylanisolvens co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                  Odoribacter splanchnicus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        4 Drugs Metabolized
                              Etodolac Click to Show/Hide the Detail
                                 Drug ID DR0666   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Odoribacter splanchnicus co-metabolize the drug Etodolac, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Odoribacter splanchnicus co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Odoribacter splanchnicus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Odoribacter splanchnicus co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                  Parabacteroides distasonis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Parabacteroides distasonis co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Parabacteroides distasonis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Naproxen Click to Show/Hide the Detail
                                 Drug ID DR1130   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Parabacteroides distasonis co-metabolize the drug Naproxen, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                  Parabacteroides johnsonii (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Parabacteroides johnsonii co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Parabacteroides johnsonii co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Parabacteroides merdae (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Losartan potassium Click to Show/Hide the Detail
                                 Drug ID DR0984   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Parabacteroides merdae co-metabolize the drug Losartan potassium, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Parabacteroides merdae co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Prevotella copri (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Prevotella copri co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
      Bacteria: Firmicutes
                  Anaerobutyricum hallii (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Anaerobutyricum hallii co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Anaerococcus hydrogenalis (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Anaerococcus hydrogenalis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Anaerostipes hadrus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Anaerostipes hadrus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Bacteroides pectinophilus (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Bacteroides pectinophilus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Blautia hansenii (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Etodolac Click to Show/Hide the Detail
                                 Drug ID DR0666   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Blautia hansenii co-metabolize the drug Etodolac, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Blautia hansenii co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Blautia luti (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Blautia luti co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Clostridioides difficile (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Clostridioides difficile co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Clostridium botulinum (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Clostridium botulinum co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Clostridium scindens (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Clostridium scindens co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Clostridium spiroforme (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Clostridium spiroforme co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Coprococcus comes (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Coprococcus comes co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Dorea formicigenerans (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Dorea formicigenerans co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Enterocloster asparagiformis (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Enterocloster asparagiformis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Enterocloster bolteae (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Enterocloster bolteae co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Enterococcus faecalis (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Enterococcus faecalis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Erysipelatoclostridium ramosum (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Erysipelatoclostridium ramosum co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Eubacterium rectale (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Eubacterium rectale co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Holdemanella biformis (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Holdemanella biformis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Hungatella hathewayi (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Hungatella hathewayi co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Lactobacillus gasseri (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Bazedoxifene Click to Show/Hide the Detail
                                 Drug ID DR0177   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Lactobacillus gasseri co-metabolize the drug Bazedoxifene, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [6]
                  Lactobacillus reuteri (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Lactobacillus reuteri co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Marvinbryantia formatexigens (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Marvinbryantia formatexigens co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Roseburia intestinalis (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Roseburia intestinalis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Ruminococcus torques (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Ruminococcus torques co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Subdoligranulum variabile (firmicutes) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Subdoligranulum variabile co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
      Bacteria: Lentisphaerae
                  Victivallis vadensis (PVC bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Victivallis vadensis co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
      Bacteria: Proteobacteria
                  Edwardsiella tarda (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Edwardsiella tarda co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Enterobacter cancerogenus (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Enterobacter cancerogenus co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Escherichia coli (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Escherichia coli co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Proteus penneri (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Proteus penneri co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Providencia alcalifaciens (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Providencia alcalifaciens co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Providencia rettgeri (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Providencia rettgeri co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Providencia stuartii (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Providencia stuartii co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                  Salmonella enterica (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Salmonella enterica co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
      Bacteria: Verrucomicrobia
                  Akkermansia muciniphila (verrucomicrobiae) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Mycophenolate mofetil Click to Show/Hide the Detail
                                 Drug ID DR1118   Drug Info
                                 Interaction Mechanism Human UDP-glucuronosyltransferase 1A10 (UGT1A10) and Akkermansia muciniphila co-metabolize the drug Mycophenolate mofetil, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
References
1 [Pharmacology of mycophenolate mofetil: recent data and clinical consequences]. Nephrologie. 2001;22(7):331-7.
2 Mapping human microbiome drug metabolism by gut bacteria and their genes. Nature. 2019 Jun;570(7762):462-467.
3 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
4 S-Naproxen and desmethylnaproxen glucuronidation by human liver microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxen. Br J Clin Pharmacol. 2005 Oct;60(4):423-33.
5 In vitro metabolism, permeability, and efflux of bazedoxifene in humans. Drug Metab Dispos. 2010 Sep;38(9):1471-9.
6 Long-term administration of conjugated estrogen and bazedoxifene decreased murine fecal beta-glucuronidase activity without impacting overall microbiome community. Sci Rep. 2018 May 25;8(1):8166.

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