Interactions between Xenobiotics and DME (XEOTIC)
|
Natural Product(s), Extract(s) or Medicine(s) |
Natural Product |
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|
Baicalein |
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Inhibition |
XEOTIC ID |
XEO01212
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Natural Product |
DME Modulation |
Baicalein inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Burkholderia multivorans |
[1] |
Cinnamic aldehyde |
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Inhibition |
XEOTIC ID |
XEO01253
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Natural Product |
DME Modulation |
Cinnamic aldehyde inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Burkholderia multivorans |
[1] |
Pharmaceutical Agent(s) |
Approved/Marketed Drug |
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|
Ceftazidime hydrate |
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Inhibition |
XEOTIC ID |
XEO02786
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Drug Marketed but not Approved by US FDA |
DME Modulation |
Ceftazidime hydrate inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Burkholderia multivorans |
[1] |
Drug in Phase 3 Clinical Trial |
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|
Curcumin |
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Inhibition |
XEOTIC ID |
XEO00683
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Highest Clinical Status: Phase 3 |
DME Modulation |
Curcumin inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Burkholderia multivorans |
[1] |
Epigallocatechin gallate |
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Inhibition |
XEOTIC ID |
XEO00613
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Highest Clinical Status: Phase 3 |
DME Modulation |
Epigallocatechin gallate inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Burkholderia multivorans |
[1] |
Resveratrol |
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Inhibition |
XEOTIC ID |
XEO00568
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Highest Clinical Status: Phase 3 |
DME Modulation |
Resveratrol inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Burkholderia multivorans |
[1] |
Preclinical/Patented Drug |
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|
Esculetin |
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Inhibition |
XEOTIC ID |
XEO01291
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Drug in Preclinical Study |
DME Modulation |
Esculetin inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Burkholderia multivorans |
[1] |
Investigative Agent |
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|
Esculin hydrate |
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Inhibition |
XEOTIC ID |
XEO03324
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Investigative Agent |
DME Modulation |
Esculin hydrate inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Burkholderia multivorans |
[1] |
Farnesol |
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Inhibition |
XEOTIC ID |
XEO01298
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Investigative Agent |
DME Modulation |
Farnesol inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Burkholderia multivorans |
[1] |
L-Canavanine |
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Inhibition |
XEOTIC ID |
XEO03812
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Investigative Agent |
DME Modulation |
L-Canavanine inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Burkholderia multivorans |
[1] |
Other Chemical Compound(s) or Element(s) |
Chemical Compound |
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|
6-Fluoroanthranilic acid |
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Inhibition |
XEOTIC ID |
XEO01933
XEOTIC Info
|
Gene Form |
Protein |
Classification |
Chemical Compound |
DME Modulation |
6-Fluoroanthranilic acid inhibits the drug-metabolizing activity of Beta-lactamase (blaB) from Burkholderia multivorans |
[1] |
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