| General Information of DME (ID: DMEN749) |
| DME Name |
Penicillin G acylase (pac), Escherichia coli
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| Gene Name |
pac
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| Lineage |
Species: Escherichia coli (Click to Show/Hide the Complete Species Lineage)
Kingdom: .
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Genus: .
Species: Escherichia coli
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Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
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| Full List of Drug(s) Metabolized by This DME |
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Drugs Approved by FDA
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Click to Show/Hide the Full List of Drugs: 2 Drugs
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Cephaloglycin |
Drug Info
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Approved |
Bacterial infection
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ICD11: 1A00-1C4Z
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[1] |
Penicillin |
Drug Info
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Approved |
Bacterial infection
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ICD11: 1A00-1C4Z
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[2] |
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| Full List of Metabolic Reactions (MR) Catalyzed by This DME |
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| References |
| 1 |
Expression of penicillin G acylase gene from Bacillus megaterium ATCC 14945 in Escherichia coli and Bacillus subtilis
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| 2 |
Ligand-induced conformational change in penicillin acylase
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| 3 |
Metabolism of penicillins to penicilloic acids and 6-aminopenicillanic acid in man and its significance in assessing penicillin absorption
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