Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008130)
Formula
pac
SVG example
Unclear
Reactant Penicillin Product 6-aminopenicillanic acid
Reactant Info Product Info
Metabolic Enzyme Penicillin G acylase (pac) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008131 Penicillin Penicilloic acid Unclear - Unclear Penicillin [1]
MR008132 Penicillin Phenylacetic acid Unclear - Unclear Penicillin [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008098 Cyclacillin 6-APA Hydrolysis - Hydrolysis Cyclacillin [3]
MR001971 Penicillin G 6-aminopenicillanic acid Unclear Penicillin G [4]
MR008106 Penicillin G Sodium 6-aminopenicillanic acid Hydrolysis - Hydrolysis Penicillin G Sodium [1]
MR008112 Penicillin V 6-aminopenicillanic acid Unclear - Unclear Penicillin V [5]
References
1 Metabolism of penicillins to penicilloic acids and 6-aminopenicillanic acid in man and its significance in assessing penicillin absorption
2 Ligand-induced conformational change in penicillin acylase
3 Sex- and species-related nephropathy of 6-(1-aminocyclohexanecarboxamido)penicillanic acid (cyclacillin) and its relationship to the metabolic disposition of the drug
4 McEvoy, G.K. (ed.). American Hospital Formulary Service - Drug Information 1999. Bethesda, MD:American Society of Health-System Pharmacists, Inc. 1999 (Plus Supplements)., p. 1760
5 Specificity of penicillin acylase of Fusarium and of Penicillium chrysogenum

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