| General Information of DME (ID: DMEN019) |
| DME Name |
Carboxylesterase (CES1A1a), Homo sapiens
|
| Gene Name |
CES1A1a
|
| UniProt ID |
|
| EC Number |
EC: 2.7.4.6 (Click to Show/Hide the Complete EC Tree)
Transferase
Kinase
Phosphotransferase
EC: 2.7.4.6
|
| Lineage |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
|
|
Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
|
| Sequence |
MWLRAFILATLSASAAW
|
|
|
|
|
|
|
| Full List of Drug(s) Metabolized by This DME |
|
Drugs Approved by FDA
|
Click to Show/Hide the Full List of Drugs: 1 Drugs
|
Dexmethylphenidate |
Drug Info
|
Approved |
Attention deficit hyperactivity disorder
|
ICD11: 6A05
|
[1] |
|
|
|
|
|
|
| Full List of Metabolic Reactions (MR) Catalyzed by This DME |
|
|
|
|
|
|
|
|
| References |
| 1 |
Methylphenidate is stereoselectively hydrolyzed by human carboxylesterase CES1A1 J Pharmacol Exp Ther. 2004 Aug;310(2):469-76. doi: 10.1124/jpet.104.067116.
|
| 2 |
Methylphenidate is stereoselectively hydrolyzed by human carboxylesterase CES1A1. J Pharmacol Exp Ther. 2004 Aug;310(2):469-76.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.
