General Information of Drug Metabolite (DM) (ID: DM000243) |
DM Name |
Lesinurad metabolite M3b
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Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
DME(s) Producing This DM through Metabolism |
DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
Cytochrome P450 2C9 (CYP2C9)
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DME0019
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| Oxidation - Hydroxylation |
Lesinurad
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[1] |
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Full List of Drug(s) That Produce This DM By Metabolism |
Lesinurad |
DR0926
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Approved |
Uncontrolled gout |
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References |
1 |
Characterization of Stereoselective Metabolism, Inhibitory Effect on Uric Acid Uptake Transporters, and Pharmacokinetics of Lesinurad Atropisomers Drug Metab Dispos. 2019 Feb;47(2):104-113. doi: 10.1124/dmd.118.080549.
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