General Information of Drug Metabolite (DM) (ID: DM000243)
DM Name
Lesinurad metabolite M3b
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 2C9 (CYP2C9) DME0019 Oxidation - Hydroxylation Lesinurad [1]
Full List of Drug(s) That Produce This DM By Metabolism
Lesinurad DR0926 Approved Uncontrolled gout
References
1 Characterization of Stereoselective Metabolism, Inhibitory Effect on Uric Acid Uptake Transporters, and Pharmacokinetics of Lesinurad Atropisomers Drug Metab Dispos. 2019 Feb;47(2):104-113. doi: 10.1124/dmd.118.080549.

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