General Information of Drug Metabolite (DM) (ID: DM000762)
DM Name
Cenobamate metabolite M2a/2b
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
UDP-glucuronosyltransferase 2B4 (UGT2B4) DME0047 Conjugation - Glucuronidation Cenobamate [1]
UDP-glucuronosyltransferase 2B7 (UGT2B7) DME0040 Conjugation - Glucuronidation Cenobamate [1]
Full List of Drug(s) That Produce This DM By Metabolism
Cenobamate DR0288 Approved Focal seizure
References
1 Mass Balance, Metabolism, and Excretion of Cenobamate, a New Antiepileptic Drug, After a Single Oral Administration in Healthy Male Subjects Eur J Drug Metab Pharmacokinet. 2020 Aug;45(4):513-522. doi: 10.1007/s13318-020-00615-7.

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