General Information of Drug Metabolite (DM) (ID: DM001445)
DM Name
Bortezomib metabolite M24
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 1A2 (CYP1A2) DME0003 Unclear - Unclear Bortezomib [1]
Cytochrome P450 2D6 (CYP2D6) DME0009 Unclear - Unclear Bortezomib [1]
Cytochrome P450 3A4 (CYP3A4) DME0001 Unclear - Unclear Bortezomib [1]
Mephenytoin 4-hydroxylase (CYP2C19) DME0021 Unclear - Unclear Bortezomib [1]
Full List of Drug(s) That Produce This DM By Metabolism
Bortezomib DR0221 Approved Breast cancer
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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