| General Information of Drug Metabolite (DM) (ID: DM002005) |
| DM Name |
Ertugliflozin metabolite M4b
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 1A3 (UGT1A3)
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DME0041
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| Conjugation - Glucuronidation |
Ertugliflozin
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[1] |
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UDP-glucuronosyltransferase 1A9 (UGT1A9)
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DME0042
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| Conjugation - Glucuronidation |
Ertugliflozin
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Ertugliflozin |
DR0604
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Approved |
Diabetes mellitus |
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| References |
| 1 |
Pharmacokinetics, metabolism, and excretion of the antidiabetic agent ertugliflozin (PF-04971729) in healthy male subjects Drug Metab Dispos. 2013 Feb;41(2):445-56. doi: 10.1124/dmd.112.049551.
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