General Information of Drug Metabolite (DM) (ID: DM003253)
DM Name
KW-5338 Metabolite M1
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 2B6 (CYP2B6) DME0020 Oxidation - Hydrolyzationn KW-5338 [1]
Cytochrome P450 3A4 (CYP3A4) DME0001 Oxidation - Hydrolyzationn KW-5338 [1]
Cytochrome P450 3A5 (CYP3A5) DME0012 Oxidation - Hydrolyzationn KW-5338 [1]
Full List of Drug(s) That Produce This DM By Metabolism
KW-5338 DR0527 Phase 3 Gastroparesis
References
1 Identification of the cytochrome P450 enzymes involved in the metabolism of domperidone. Xenobiotica. 2004 Nov-Dec;34(11-12):1013-23.

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