| General Information of Drug Metabolite (DM) (ID: DM003253) |
| DM Name |
KW-5338 Metabolite M1
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2B6 (CYP2B6)
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DME0020
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| Oxidation - Hydrolyzationn |
KW-5338
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[1] |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - Hydrolyzationn |
KW-5338
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[1] |
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Cytochrome P450 3A5 (CYP3A5)
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DME0012
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| Oxidation - Hydrolyzationn |
KW-5338
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| KW-5338 |
DR0527
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Phase 3 |
Gastroparesis |
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| References |
| 1 |
Identification of the cytochrome P450 enzymes involved in the metabolism of domperidone. Xenobiotica. 2004 Nov-Dec;34(11-12):1013-23.
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