| General Information of Drug Metabolite (DM) (ID: DM004658) |
| DM Name |
Tipranavir Metabolite
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2D6 (CYP2D6)
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DME0009
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| Oxidation - Monohydroxylation |
Tipranavir
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[1] |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - Monohydroxylation |
Tipranavir
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[1] |
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Mephenytoin 4-hydroxylase (CYP2C19)
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DME0021
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| Oxidation - Monohydroxylation |
Tipranavir
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Tipranavir |
DR1601
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Approved |
Human immunodeficiency virus infection |
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| References |
| 1 |
Metabolism-mediated drug interactions associated with ritonavir-boosted tipranavir in mice. Drug Metab Dispos. 2010 May;38(5):871-8.
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