| General Information of Drug Metabolite (DM) (ID: DM004991) |
| DM Name |
Dihydroartemisinin Glucuronide
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 1A9 (UGT1A9)
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DME0042
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| Unclear - Unclear |
Artesunate
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[1] , [2] |
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UDP-glucuronosyltransferase 2B7 (UGT2B7)
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DME0040
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| Unclear - Unclear |
Artesunate
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Artesunate |
DR5926
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Approved |
Malaria |
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| References |
| 1 |
Glucuronidation of dihydroartemisinin in vivo and by human liver microsomes and expressed UDP-glucuronosyltransferases
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| 2 |
LC-MS/MS method for the simultaneous quantification of artesunate and its metabolites dihydroartemisinin and dihydroartemisinin glucuronide in human plasma
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