| General Information of Drug Metabolite (DM) (ID: DM005004) |
| DM Name |
M690
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Cytochrome P450 2C9 (CYP2C9)
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DME0019
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| Conjugation - Hydroxy glucuronidation |
Avapritinib
|
[1] |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Conjugation - Hydroxy glucuronidation |
Avapritinib
|
[1] |
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Cytochrome P450 3A5 (CYP3A5)
|
DME0012
|
| Conjugation - Hydroxy glucuronidation |
Avapritinib
|
[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Avapritinib |
DR5452
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Approved |
Gastrointestinal stromal tumour |
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| Dezocine |
DR5229
|
Approved |
Pain |
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| References |
| 1 |
FDA label:Avapritinib
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