General Information of Drug Metabolite (DM) (ID: DM005346)
DM Name
OH-dehydroxyzileuton
Structure
3D MOL is unavailable 2D MOL is unavailable
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 1A2 (CYP1A2) DME0003 Oxidation - Hydrolyzationn Zileuton [1] , [2]
Cytochrome P450 2C9 (CYP2C9) DME0019 Oxidation - Hydrolyzationn Zileuton [1] , [2]
Full List of Drug(s) That Produce This DM By Metabolism
Zileuton DR1730 Approved Asthma
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
2 Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development. Curr Med Chem. 2009;16(31):4066-218.

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