| General Information of Drug Metabolite (DM) (ID: DM005999) |
| DM Name |
O-Desmethylvicriviroc
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| PubChem CID |
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2C9 (CYP2C9)
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DME0019
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| Oxidation - O-demethylation |
SCH-417690
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[1] |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - O-demethylation |
SCH-417690
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[1] |
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Cytochrome P450 3A5 (CYP3A5)
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DME0012
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| Oxidation - O-demethylation |
SCH-417690
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| SCH-417690 |
DR1683
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Phase 3 |
Human immunodeficiency virus infection |
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| References |
| 1 |
Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
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