| General Information of Drug Metabolite (DM) (ID: DM006597) |
| DM Name |
Dihydrocodeine-6-glucuronide
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 2B4 (UGT2B4)
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DME0047
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| Conjugation - Glucuronidation |
Dihydrocodeine
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[1] , [2] |
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UDP-glucuronosyltransferase 2B7 (UGT2B7)
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DME0040
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| Conjugation - Glucuronidation |
Dihydrocodeine
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Dihydrocodeine |
DR0500
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Phase 4 |
Anaesthesia |
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| References |
| 1 |
Pharmacokinetics of dihydrocodeine and its active metabolite after single and multiple oral dosing. Br J Clin Pharmacol. 1999 Sep;48(3):317-22.
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| 2 |
Adult and infant pharmacokinetic profiling of dihydrocodeine using physiologically based pharmacokinetic modeling. Biopharm Drug Dispos. 2019 Nov;40(9):350-357.
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