Details of the Drug Metabolite (DM)

General Information of Drug Metabolite (DM) (ID: DM017125)
DM Name
BIA 9-1106
Structure
3D MOL is unavailable 2D MOL is unavailable
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
UDP-glucuronosyltransferase 1A1 (UGT1A1) DME0004
Opicapone
Conjugation - Glucuronidation Opicapone [1]
UDP-glucuronosyltransferase 1A3 (UGT1A3) DME0041
Opicapone
Conjugation - Glucuronidation Opicapone [1]
UDP-glucuronosyltransferase 1A6 (UGT1A6) DME0072
Opicapone
Conjugation - Glucuronidation Opicapone [1]
UDP-glucuronosyltransferase 2B15 (UGT2B15) DME0049
Opicapone
Conjugation - Glucuronidation Opicapone [1]
UDP-glucuronosyltransferase 2B7 (UGT2B7) DME0040
Opicapone
Conjugation - Glucuronidation Opicapone [1]
Full List of Drug(s) That Produce This DM By Metabolism
Opicapone DR5385 Approved Parkinsonism
References
1 Pharmacokinetics, pharmacodynamics and tolerability of opicapone, a novel catechol-O-methyltransferase inhibitor, in healthy subjects: prediction of slow enzyme-inhibitor complex dissociation of a short-living and very long-acting inhibitor

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