| General Information of Drug Metabolite (DM) (ID: DM017467) |
| DM Name |
Arbidol M7 metabolite
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Multi-steps Reaction - N-demethylation; sulfoxidation |
Arbidol
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[1] |
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Dimethylaniline oxidase 1 (FMO1)
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DME0059
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| Multi-steps Reaction - N-demethylation; sulfoxidation |
Arbidol
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[1] |
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| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 1A9 (UGT1A9)
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DME0042
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| Conjugation - O-glucuronidation |
Arbidol
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[2] |
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UDP-glucuronosyltransferase 2B7 (UGT2B7)
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DME0040
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| Conjugation - O-glucuronidation |
Arbidol
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[2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Arbidol |
DR5473
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Approved |
Virus infection |
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| References |
| 1 |
Pharmacokinetics, metabolism, and excretion of the antiviral drug arbidol in humans
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| 2 |
DrugBank(Pharmacology-Metabolism):Arbidol
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