| General Information of Drug Metabolite (DM) (ID: DM017811) |
| DM Name |
TAK-802 Metabolite M-IV
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1)
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DME0199
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| Reduction - Reduction |
TAK-802
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[1] |
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| DME(s) Metabolizing This DM |
| DME Name |
DME ID |
Product |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2B6 (CYP2B6)
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DME0020
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| Unclear - Unclear |
TAK-802
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[1] |
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Cytochrome P450 2E1 (CYP2E1)
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DME0013
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| Unclear - Unclear |
TAK-802
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[1] |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Unclear - Unclear |
TAK-802
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| TAK-802 |
DR2997
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Discontinued in Phase 2 |
Urinary dysfunction |
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| References |
| 1 |
Main metabolic pathways of TAK-802, a novel drug candidate for voiding dysfunction, in humans: the involvement of carbonyl reduction by 11-hydroxysteroid dehydrogenase 1
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