| General Information of Drug Metabolite (DM) (ID: DM018195) |
| DM Name |
(+)-JQ1 Metabolite M1
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2C9 (CYP2C9)
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DME0019
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| Unclear - Unclear |
(+)-JQ1
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[1] |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Unclear - Unclear |
(+)-JQ1
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[1] |
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Mephenytoin 4-hydroxylase (CYP2C19)
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DME0021
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| Unclear - Unclear |
(+)-JQ1
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| (+)-JQ1 |
DR3111
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Phase 1 |
Testicular cancer |
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| References |
| 1 |
Metabolism of JQ1, an inhibitor of bromodomain and extra terminal bromodomain proteins, in human and mouse liver microsomes?
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