| General Information of Drug Metabolite (DM) (ID: DM019050) |
| DM Name |
ABT-107 Metabolite M2
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 1A2 (CYP1A2)
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DME0003
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| Unclear - Unclear |
ABT-107
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[1] |
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Cytochrome P450 2D6 (CYP2D6)
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DME0009
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| Unclear - Unclear |
ABT-107
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[1] |
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Cytochrome P450 2J2 (CYP2J2)
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DME0031
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| Unclear - Unclear |
ABT-107
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[1] |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Unclear - Unclear |
ABT-107
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[1] |
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Cytochrome P450 3A5 (CYP3A5)
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DME0012
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| Unclear - Unclear |
ABT-107
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| ABT-107 |
DR2917
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Discontinued in Phase 1 |
Attention deficit hyperactivity disorder |
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| References |
| 1 |
Species-dependent metabolism of a novel selective 7 neuronal acetylcholine receptor agonist ABT-107
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