| General Information of Drug Metabolite (DM) (ID: DM019537) |
| DM Name |
PF-04965842 Metabolites M1
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Cytochrome P450 2C9 (CYP2C9)
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DME0019
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| Unclear - Unclear |
PF-04965842
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[1] |
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Mephenytoin 4-hydroxylase (CYP2C19)
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DME0021
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| Unclear - Unclear |
PF-04965842
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| PF-04965842 |
DR3486
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Phase 3 |
Atopic dermatitis |
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| References |
| 1 |
The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Abrocitinib, a Selective Janus Kinase Inhibitor, in Humans
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