General Information of Drug Metabolite (DM) (ID: DM019727)
DM Name
AKB-9778 M4
Structure
3D MOL is unavailable 2D MOL is unavailable
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Metabolizing This DM
DME Name DME ID Product Reaction Related Drug REF
Cytochrome P450 2C8 (CYP2C8) DME0018 Conjugation - S-methylation AKB-9778 [1]
Full List of Drug(s) That Produce This DM By Metabolism
AKB-9778 DR3319 Phase 2 Arterial occlusive disease
References
1 Oxidative metabolism of razuprotafib (AKB-9778), a sulfamic acid phosphatase inhibitor, in human microsomes and recombinant human CYP2C8 enzyme

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