| General Information of Drug Metabolite (DM) (ID: DM019728) |
| DM Name |
AKB-9778 M5
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2C8 (CYP2C8)
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DME0018
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| Conjugation - S-methylation |
AKB-9778
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| AKB-9778 |
DR3319
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Phase 2 |
Arterial occlusive disease |
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| References |
| 1 |
Oxidative metabolism of razuprotafib (AKB-9778), a sulfamic acid phosphatase inhibitor, in human microsomes and recombinant human CYP2C8 enzyme
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