General Information of Drug Metabolite (DM) (ID: DM019802)
DM Name
PT2385 M11
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
UDP-glucuronosyltransferase 1A1 (UGT1A1) DME0004 Multi-steps Reaction - Hydroxylation; Glucuronide conjugation PT2385 [1]
UDP-glucuronosyltransferase 1A3 (UGT1A3) DME0041 Multi-steps Reaction - Hydroxylation; Glucuronide conjugation PT2385 [1]
UDP-glucuronosyltransferase 1A9 (UGT1A9) DME0042 Multi-steps Reaction - Hydroxylation; Glucuronide conjugation PT2385 [1]
UDP-glucuronosyltransferase 2B15 (UGT2B15) DME0049 Multi-steps Reaction - Hydroxylation; Glucuronide conjugation PT2385 [1]
UDP-glucuronosyltransferase 2B17 (UGT2B17) DME0066 Multi-steps Reaction - Hydroxylation; Glucuronide conjugation PT2385 [1]
Full List of Drug(s) That Produce This DM By Metabolism
PT2385 DR3296 Phase 2 Von hippel-lindau disease
References
1 Metabolic Profiling of the Novel Hypoxia-Inducible Factor 2 Inhibitor PT2385 In Vivo and In Vitro

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.