| General Information of Drug Metabolite (DM) (ID: DM000491) |
| DM Name |
Hydroxy-piperidine temsirolimus
|
|
|
|
|
|
|
|
| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Cytochrome P450 2C8 (CYP2C8)
|
DME0018
|
| Oxidation - Hydroxylation |
Temsirolimus
|
[1] |
|
Cytochrome P450 3A5 (CYP3A5)
|
DME0012
|
| Oxidation - Hydroxylation |
Temsirolimus
|
[1] |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Full List of Drug(s) That Produce This DM By Metabolism |
| Temsirolimus |
DR1548
|
Approved |
Renal cell carcinoma |
|
|
| References |
| 1 |
Temsirolimus metabolic pathways revisited Xenobiotica. 2020 Jun;50(6):640-653. doi: 10.1080/00498254.2019.1678793.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.
