| General Information of Drug Metabolite (DM) (ID: DM005346) |
| DM Name |
OH-dehydroxyzileuton
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 1A2 (CYP1A2)
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DME0003
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| Oxidation - Hydrolyzationn |
Zileuton
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[1] , [2] |
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Cytochrome P450 2C9 (CYP2C9)
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DME0019
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| Oxidation - Hydrolyzationn |
Zileuton
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Zileuton |
DR1730
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Approved |
Asthma |
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| References |
| 1 |
Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
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| 2 |
Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development. Curr Med Chem. 2009;16(31):4066-218.
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