| General Information of Drug Metabolite (DM) (ID: DM005463) |
| DM Name |
2-OH-GTS-21
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 1A2 (CYP1A2)
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DME0003
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| Oxidation - O-demethylation |
GTS-21
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[1] |
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Cytochrome P450 2E1 (CYP2E1)
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DME0013
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| Oxidation - O-demethylation |
GTS-21
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[1] |
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Cytochrome P450 3A (CYP3A)
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DMEN065
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| Oxidation - O-demethylation |
GTS-21
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| GTS-21 |
DR0792
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Phase 2 |
Schizophrenia |
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| References |
| 1 |
Metabolism and disposition of GTS-21, a novel drug for Alzheimer's disease. Xenobiotica. 1999 Jul;29(7):747-62.
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