| General Information of Drug Metabolite (DM) (ID: DM018052) |
| DM Name |
Avanafil Metabolite M1
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| Structure |
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3D MOL is unavailable
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2D MOL is unavailable
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2C9 (CYP2C9)
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DME0019
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| Unclear - Unclear |
Avanafil
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[1] , [2] |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Unclear - Unclear |
Avanafil
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Avanafil |
DR0159
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Approved |
Erectile dysfunction |
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| References |
| 1 |
LC-MS/MS determination of avanafil and its metabolites in rat plasma and brain: pharmacokinetic study after oral administration and transdermal film application
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| 2 |
FDA:Avanafil
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