General Information of Drug Metabolite (DM) (ID: DM018966)
DM Name
LNP023 Metabolite M4
Structure
3D MOL is unavailable 2D MOL is unavailable
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Metabolizing This DM
DME Name DME ID Product Reaction Related Drug REF
Cytochrome P450 2C8 (CYP2C8) DME0018 Oxidation - Oxidation LNP023 [1] , [2]
Full List of Drug(s) That Produce This DM By Metabolism
LNP023 DR3488 Phase 3 IgA nephropathy
References
1 Pharmacokinetics and metabolism of LNP023 in rats by liquid chromatography combined with electrospray ionization-tandem mass spectrometry
2 Absorption, Distribution, Metabolism, and Excretion of [(14)C]iptacopan in Healthy Male Volunteers and in In Vivo and In Vitro Studies

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