Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000037)
Formula Reactant O-desmethyl-des-4-chlorobenzoyl Product O-desmethyl-des-4-chlorobenzoyl glucuronide
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 2B7 (UGT2B7) DME Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000041 Acemetacin O-desmethyl-des-4-chlorobenzoyl Oxidation - Demethylation Acemetacin [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000038 O-desmethyl-des-4-chlorobenzoyl Des-p-chlorobenzoyl-O-desmethylindometacinsulfate Unclear Acemetacin [2]
References
1 DrugBank(Pharmacology-Metabolism)Acemetacin
2 [Comparative metabolic studies on [14C]-labelled acemetacin and indometacin in rats (author's transl)] Arzneimittelforschung. 1980;30(8A):1384-91.

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