Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000066)
Formula
SVG example
Reactant Ademetionine Product Cysteine
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000065 Ademetionine Cystathionine Unclear Ademetionine [1]
MR000067 Ademetionine Homocysteine Unclear Ademetionine [1]
MR000069 Ademetionine Methionine Unclear Ademetionine [1]
MR000068 Ademetionine S-Adenosylhomocysteine Unclear Ademetionine [2], [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007364 BRN-4179169 Cysteine Unclear BRN-4179169 [3]
MR007539 Benzylamine M3 Cysteine Unclear Benzylamine [4]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007365 Cysteine Cysteamine Unclear BRN-4179169 [3]
MR007368 Cysteine Cysteine sulfate Unclear BRN-4179169 [3]
References
1 DrugBank(Pharmacology-Metabolism)Ademetionine
2 Kinetic Mechanism of Nicotinamide N-Methyltransferase Biochemistry. 2018 Sep 25;57(38):5524-5532. doi: 10.1021/acs.biochem.8b00775.
3 Non-invasive monitoring of L-2-oxothiazolidine-4-carboxylate metabolism in the rat brain by in vivo 13C magnetic resonance spectroscopy
4 Bioactivation of benzylamine to reactive intermediates in rodents: formation of glutathione, glutamate, and peptide conjugates

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