General Information of This Metabolic Reaction (MR) (ID: MR000069)
Formula
SVG example
Reactant Ademetionine Product Methionine
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000065 Ademetionine Cystathionine Unclear Ademetionine [1]
MR000066 Ademetionine Cysteine Unclear Ademetionine [1]
MR000067 Ademetionine Homocysteine Unclear Ademetionine [1]
MR000068 Ademetionine S-Adenosylhomocysteine Unclear Ademetionine [2], [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004273 2-Keto-4-methylthiobutyrate Methionine Unclear Methylthioribose phosphate [3]
MR004268 MTR-1-P Methionine Unclear Methylthioadenosine [4]
MR003670 Betaine Methionine Unclear IP-302 [5]
MR001082 5-Methyltetrahydrofolate Methionine Unclear Folic acid [6]
References
1 DrugBank(Pharmacology-Metabolism)Ademetionine
2 Kinetic Mechanism of Nicotinamide N-Methyltransferase Biochemistry. 2018 Sep 25;57(38):5524-5532. doi: 10.1021/acs.biochem.8b00775.
3 The metabolism of 5'-methylthioadenosine and 5-methylthioribose 1-phosphate in Saccharomyces cerevisiae
4 Targeting tumors that lack methylthioadenosine phosphorylase (MTAP) activity: current strategies
5 Metabolism and actions of CDP-choline as an endogenous compound and administered exogenously as citicoline
6 DrugBank(Pharmacology-Metabolism)Folic acid

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