Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000083)
Formula
SVG example
Reactant Inosine Product Adenosine phosphate metabolite Hx (hypoxanthine)
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007507 Inosine Hypoxanthine Unclear Inosine [1], [2]
MR007514 Inosine IMP Unclear Inosine [1], [2]
MR007513 Inosine Unclear Unclear Inosine [1], [2]
MR000078 Inosine Hypoxanthine Other reaction - Phosphorylation Adenosine [3], [4]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011010 Mizoribine Hypoxanthine arabinoside Unclear - Unclear Mizoribine [5]
MR011013 Vidarabine Hypoxanthine arabinoside Unclear - Unclear Vidarabine [5]
References
1 Metabolism of nicotinamide, adenine and inosine in developing microspore-derived canola (Brassica napus) embryos
2 Inosine in Biology and Disease
3 Adenosine Metabolism: Emerging Concepts for Cancer Therapy Cancer Cell. 2019 Dec 9;36(6):582-596. doi: 10.1016/j.ccell.2019.10.007.
4 Purine signaling pathway dysfunction in autism spectrum disorders: Evidence from multiple omics data. Front Mol Neurosci. 2023 Feb 3;16:1089871. doi: 10.3389/fnmol.2023.1089871.
5 Effect of a novel adenosine deaminase inhibitor (co-vidarabine, co-V) upon the antiviral activity in vitro and in vivo of vidarabine (Vira-Atm) for DNA virus replication

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