Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000095)
Formula
CBR1 ...
SVG example
Reactant Adriamycin Product Doxorubicinol
Reactant Info Product Info
Metabolic Enzyme NADPH-dependent carbonyl reductase 1 (CBR1) DME Info
Aldo-keto reductase 1C3 (AKR1C3) DME Info
Aldo-keto reductase 1A1 (AKR1A1) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000096 Adriamycin Doxorubicin aglycone Unclear Adriamycin [1]
MR000094 Adriamycin Doxorubicin-semiquinone Unclear Adriamycin [1]
MR000093 Adriamycin Doxorubicinol deoxaglycone Unclear Adriamycin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006675 Doxorubicin Doxorubicinol Unclear Doxorubicin [2]
References
1 Pharmacogenomics knowledge for personalized medicine Clin Pharmacol Ther. 2012 Oct;92(4):414-7. doi: 10.1038/clpt.2012.96.
2 PharmGKB:Doxorubicin

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.