Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000094)
Formula
NOS3 ...
SVG example
Reactant Adriamycin Product Doxorubicin-semiquinone
Reactant Info Product Info
Metabolic Enzyme Nitric oxide synthase, endothelial (NOS3) DME Info
Nitric oxide synthase, inducible (NOS2) DME Info
Nitric oxide synthase, brain (NOS1) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000096 Adriamycin Doxorubicin aglycone Unclear Adriamycin [1]
MR000095 Adriamycin Doxorubicinol Unclear Adriamycin [1]
MR000093 Adriamycin Doxorubicinol deoxaglycone Unclear Adriamycin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006676 Doxorubicin Doxorubicin-semiquinone Unclear Doxorubicin [2]
References
1 Pharmacogenomics knowledge for personalized medicine Clin Pharmacol Ther. 2012 Oct;92(4):414-7. doi: 10.1038/clpt.2012.96.
2 PharmGKB:Doxorubicin

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