Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000104)
Formula Reactant Agomelatine Product Agomelatine metabolite M1
Reactant Info Product Info
Metabolic Type Oxidation - Monohydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000103 Agomelatine Agomelatine metabolite M5 Oxidation - Demethylation Agomelatine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000102 Agomelatine metabolite M1 Agomelatine metabolite M37 Oxidation - Dealkylation Agomelatine [1]
References
1 Characterizing novel metabolic pathways of melatonin receptor agonist agomelatine using metabolomic approaches Biochem Pharmacol. 2016 Jun 1;109:70-82. doi: 10.1016/j.bcp.2016.03.020.

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