Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000119)
Formula
CYP
SVG example
O-Demethylation
Reactant Noralfentanil Product Alfentanil metabolite AM6
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 (CYP) DME Info
Metabolic Type Oxidation - O-Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000122 Alfentanil Noralfentanil Oxidation - N-Dealkylation Alfentanil [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000120 Noralfentanil Alfentanil metabolite AM5 Oxidation - Oxidation Alfentanil [2]
References
1 Metabolism of alfentanil by cytochrome p4503a (cyp3a) enzymes. Drug Metab Dispos. 2005 Mar;33(3):303-11.
2 Alfentanil pharmacokinetics and metabolism in humans Anesthesiology. 1988 Oct;69(4):527-34. doi: 10.1097/00000542-198810000-00012.

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