Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000120)
Formula
CYP
SVG example
Oxidation
Reactant Noralfentanil Product Alfentanil metabolite AM5
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 (CYP) DME Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000122 Alfentanil Noralfentanil Oxidation - N-Dealkylation Alfentanil [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000119 Noralfentanil Alfentanil metabolite AM6 Oxidation - O-Demethylation Alfentanil [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000123 Alfentanil Alfentanil metabolite AM5 Oxidation - Oxidation Alfentanil [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000121 Alfentanil metabolite AM5 Alfentanil metabolite AM3 Hydrolysis - Amid Hydrolysis; Acetylation Alfentanil [2]
References
1 Metabolism of alfentanil by cytochrome p4503a (cyp3a) enzymes. Drug Metab Dispos. 2005 Mar;33(3):303-11.
2 Alfentanil pharmacokinetics and metabolism in humans Anesthesiology. 1988 Oct;69(4):527-34. doi: 10.1097/00000542-198810000-00012.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.