Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000128)
Formula
SVG example
Oxidation
Reactant Aliskiren metabolite M3 Product Aliskiren metabolite M2
Reactant Info Product Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000132 Aliskiren Aliskiren metabolite M3 Oxidation - O-Demethylation Aliskiren [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000129 Aliskiren metabolite M3 Aliskiren metabolite M4 Oxidation - O-Dealkylation Aliskiren [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000130 Aliskiren metabolite M2 Aliskiren metabolite M4 Oxidation - O-Dealkylation Aliskiren [1]
References
1 Absorption, distribution, metabolism, and elimination of the direct renin inhibitor aliskiren in healthy volunteers Drug Metab Dispos. 2007 Aug;35(8):1418-28. doi: 10.1124/dmd.106.013797.

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