Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000207)
Formula Reactant Amoxapine Product N-Formyl-7-hydroxyamoxapine
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000205 Amoxapine 7-hydroxyamoxapine Oxidation - Hydroxylation Amoxapine [1], [2]
MR000206 Amoxapine 8-hydroxyamoxapine Oxidation - Hydroxylation Amoxapine [1], [2]
MR000208 Amoxapine N-Formylamoxapine Unclear Amoxapine [3]
References
1 Addition of amoxapine improves positive and negative symptoms in a patient with schizophrenia. Ther Adv Psychopharmacol. 2013 Dec;3(6):340-2.
2 DrugBank(Pharmacology-Metabolism)Amoxapine
3 Transformation of amoxapine by Cunninghamella elegans Appl Environ Microbiol. 2000 Aug;66(8):3646-9. doi: 10.1128/AEM.66.8.3646-3649.2000.

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