Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000300)
Formula
SVG example
Reactant Artemether Product Alpha-dihydroartemisinin
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2B6 (CYP2B6) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000299 Artemether 9,10-dihydrodeoxy-artemsinin Unclear Artemether [1]
MR000301 Artemether Deoxyartemsinin Unclear Artemether [1]
MR000302 Artemether Deoxydihydro-artemisinin Unclear Artemether [1]
MR000298 Artemether Dihydroartemisinin Oxidation - Oxidation Artemether [2]
References
1 DrugBank(Pharmacology-Metabolism)Artemether
2 Use of a physiologically-based pharmacokinetic model to simulate artemether dose adjustment for overcoming the drug-drug interaction with efavirenz In Silico Pharmacol. 2013 Mar 1;1:4. doi: 10.1186/2193-9616-1-4.

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