General Information of This Metabolic Reaction (MR) (ID: MR000315)
Formula
SVG example
Reactant 2,3-dikeogulonic acid Product Deoxydihydro-artemisinin
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000320 Dehydroascorbate 2,3-dikeogulonic acid Unclear Ascorbic acid [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000316 2,3-dikeogulonic acid Erythrulose Unclear Ascorbic acid [1], [2]
MR000317 2,3-dikeogulonic acid Oxalic acid Unclear Ascorbic acid [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000302 Artemether Deoxydihydro-artemisinin Unclear Artemether [3]
MR008682 Dihydroqinghaosu (DQHS) Deoxydihydro-artemisinin Unclear - Unclear Arteether [4]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008683 Deoxydihydro-artemisinin Arteether Metabolite M1 Oxidation - Hydroxylation Arteether [4]
References
1 Ascorbic acid intake and oxalate synthesis Urolithiasis. 2016 Aug;44(4):289-97. doi: 10.1007/s00240-016-0868-7.
2 Potential of (1)H NMR fingerprinting and a model system approach to study non-enzymatic browning in shelf-stable orange juice during storage. Food Res Int. 2021 Feb;140:110062. doi: 10.1016/j.foodres.2020.110062.
3 DrugBank(Pharmacology-Metabolism)Artemether
4 Synthesis, characterization, and antimalarial activity of the glucuronides of the hydroxylated metabolites of arteether

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