Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR000332)
Formula	N-Dealkylation
	Reactant	Astemizole		Product	2-(4-hydroxyphenyl)acetaldehyde
	Reactant	Reactant Info		Product	Product Info
Metabolic Type	Oxidation - N-Dealkylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR000331	Astemizole	6-hydroxyastemizole	Oxidation - Hydroxylation	Astemizole	[1]
MR000333	Astemizole	Desmethylastemizole	Oxidation - O-Demethylation	Astemizole	[2]

References
1	Involvement of multiple human cytochromes P450 in the liver microsomal metabolism of astemizole and a comparison with terfenadine. Br J Clin Pharmacol. 2001 Feb;51(2):133-42.
2	DrugBank(Pharmacology-Metabolism)Astemizole

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.