Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000363)
Formula Reactant Bicalutamide Product Hydroxy(R)bicalutamide
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000364 Bicalutamide S-bicalutamide-glucuronide Unclear Bicalutamide [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000362 Hydroxy(R)bicalutamide R-bicalutamide-glucuronide Unclear Bicalutamide [1], [2]
References
1 Enantiomer selective glucuronidation of the non-steroidal pure anti-androgen bicalutamide by human liver and kidney: role of the human UDP-glucuronosyltransferase (UGT)1A9 enzyme Basic Clin Pharmacol Toxicol. 2013 Aug;113(2):92-102. doi: 10.1111/bcpt.12071.
2 Dailymed:Bicalutamide

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